rhabdomyolysis advances in diagnosis and treatment pdf

Rhabdomyolysis Advances In Diagnosis And Treatment Pdf

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During recent years, we have witnessed many technological advances in electronic publication. The accessibility and wide diffusion of on-line publication will provide the opportunity for our scientific colleagues, not only in Latin America, but throughout the world, to share the knowledge and skills of our Mexican surgical community, as well as to provide authors from other countries with a forum for participating in our Journal, in order that we may gain knowledge of surgical specialties throughout the world.

It was created in December with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Since its foundation, the Journal has been characterized by its plurality with subjects of all rheumatic and osteomuscular pathologies, in the form of original articles, historical articles, economic evaluations, and articles of reflection and education in Medicine. It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity both in pediatric and adult pathologies , to aspects of basic sciences. It is an academic tool for the different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter-and transdisciplinarily. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad.

Rhabdomyolysis: advances in diagnosis and treatment

Key words:. Update review of the acute porphyrias. Br J Haematol ; 4 Role of genetic testing in the management of patients with inherited porphyria and their families. Ann Clin Biochem ;50 Pt 3 The incidence of inherited porphyrias in Europe. J Inherit Metab Dis ;36 5

Rhabdomyolysis is a potentially life-threatening condition caused by a breakdown of skeletal muscle and the release of the intracellular contents into the circulatory system. There are many possible causes, including crush injury, excessive muscular activity, medications, infections, and varied metabolic, connective tissue, rheumatologic, and endocrine disorders. Optimal crystalloid selection is still debated, but immediate, aggressive intravenous volume expansion is indicated to prevent myoglobinuric renal failure. Serum potassium levels must be obtained and electrocardiograms must be evaluated to identify life- and limb-threatening complications of hyperkalemia. This review examines the current evidence on symptoms and diagnostic methods as well as standard first-line treatments of rhabdomyolysis.

Rhabdomyolysis: advances in diagnosis and treatment.

Rhabdomyolysis is a common cause of acute kidney injury, featuring muscle pain, weakness and dark urine and concurrent laboratory evidence of elevated muscle enzymes and myoglobinuria. Rhabdomyolysis is often seen in elderly and frail patients following prolonged immobilization, for example after a fall, but a variety of other causes are also well-described. What is unknown to most physicians dealing with such patients is the fascinating history of rhabdomyolysis. Cases of probable rhabdomyolysis have been reported since biblical times and during antiquity, often in the context of poisoning. Equally interesting is the link between rhabdomyolysis and armed conflict during the 20th century. Salient discoveries regarding the pathophysiology, diagnosis and treatment were made during the two world wars and in their aftermath.

Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. Corpus ID: Rhabdomyolysis: advances in diagnosis and treatment. Care and C. Care , C.

THE relationship between hypermetabolic exertional stress injuries and malignant hyperthermia MH has been a topic of debate for almost 30 yr. Central to this debate is the idea that some MH susceptible MHS patients may develop awake nonanesthesia-related manifestations similar to that seen in porcine stress syndrome. An individual is identified as MHS if he or she has a well-documented clinical episode consistent with MH during exposure to any of the known anesthetic triggering agents, or if he or she has undergone a skeletal muscle biopsy with a positive diagnostic contracture test. However, none of the published reports of patients who presented first with ER and who were subsequently identified as MHS by a positive contracture test ever developed documented clinical MH episodes involving anesthesia. First, it is the only documented case of an individual who presented first with ER, followed by a clinical MH episode during anesthesia, and then by a positive contracture test. This report provides clinical evidence for an association between ER and MH and discusses the possible role for synergistic action among rare variants in the genes encoding proteins crucial to skeletal muscle calcium regulation. A physically fit, muscular, yr-old, kg African American presented to the emergency department with intense bilateral calf pain after a 2.

What's to know about rhabdomyolysis?

Vascular injury is a rare complication of femoral shaft fractures, and rupture of the deep femoral artery is more difficult to diagnose because of its anatomical location and symptoms. Despite its low incidence, deep femoral artery rupture can lead to life-threatening outcomes, such as compartment syndrome, making early identification and diagnosis critical. A year-old male patient was admitted to our hospital due to right lower limb trauma in a car accident, with complaints of severe pain and swelling on his right thigh.

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1 Comments

  1. Sven A.

    Rhabdomyolysis is a condition in which skeletal muscle tissue dies, releasing substances into the blood that cause kidney failure.

    11.06.2021 at 15:45 Reply

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